WITHDRAWN: Preparation and optimization of fenofibrate loaded self-microemulsifying drug delivery system (SMEDDS) by application of Box–Behnken design

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Preparation and Evaluation of Novel Fenofibrate-loaded Self-Microemulsifying Drug Delivery System (SMEDDS)

− Fenofibrate has been used for many years to lower cholesterol levels and its pharmacokinetic profile is well understood. However, due to its low solubility in water, it has low bioavailability after oral administration. In order to improve the dissolution rate, fenofibrate was formulated into a self-microemulsifying drug delivery systems (SMEDDS). We used pseudo-ternary phase diagrams to eval...

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A Self-microemulsifying Drug Delivery System (smedds)

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ژورنال

عنوان ژورنال: Asian Journal of Pharmaceutical Sciences

سال: 2015

ISSN: 1818-0876

DOI: 10.1016/j.ajps.2015.11.057